Asunra 400mg Tablet 6'S
Key Information
Generic Name
Generic Name Deferasirox 400 mg
Manufacturer
Novartis Healthcare Pvt Ltd
Variant
6 Tablet(s) in a Strip
Country of Origin
India
Detailed Information
Introduction
ASUNRA 400MG TABLET contains Deferasirox which belongs to the group of medicines called Iron chelators. ASUNRA 400MG TABLET is used to remove chronic iron overload (excess iron in the body) caused by frequent blood transfusions in patients with Beta thalassemia major aged 6 years and older. ASUNRA 400MG TABLET is also used to manage chronic iron overload when deferoxamine therapy is contraindicated or inadequate in patients with beta thalassaemia major and other types of anaemia with iron overload caused by repeated blood transfusions and in children 2 to 5 years of age. ASUNRA 400MG TABLET is also used when deferoxamine therapy is contraindicated or inadequate for patients aged 10 years or older who have iron overload associated with non-transfusion-dependent thalassaemia syndromes. Your doctor may advise you to undergo relevant tests to analyze your existing condition and monitor your kidney and liver function during management. ASUNRA 400MG TABLET is not recommended for use in patients with moderate to severe kidney disease, severe liver disease, advanced stage of myelodysplastic syndrome (decreased production of blood cells by the bone marrow) or advanced stage of cancer. Inform your doctor if you have heart disease. ASUNRA 400MG TABLET is generally not recommended for use by pregnant and breastfeeding women, unless recommended by your doctor. ASUNRA 400MG TABLET is not recommended for use in children under 2 years of age. The most common
Uses
OF ASUNRA 400MG TABLETIt is used to manage: chronic iron overload due to blood transfusion (transfusional haemo
How It Works
ASUNRA 400MG TABLET works by trapping and removing excess iron from the body, which is then excreted mainly in the form of stools and reduces the risk of organ damage to the liver and heart. As a result, ASUNRA 400MG TABLET helps to remove excess iron from the body.
Directions for Use
Take ASUNRA 400MG TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your physician will decide the correct dose and duration for you depending upon your age, body weight, and disease condition.
Side Effects
taking ASUNRA 400MG TABLET are nausea, vomiting, diarrhoea, abdominal pain, bloating, constipation, indigestion, rash, itching, headache, and change in liver or kidney function tests or urine tests. Consult your physician if any of your side effects get worse or persists for a longer duration. USES OF ASUNRA 400MG TABLETIt is used to manage: chronic iron overload due to blood transfusion (transfusional haemosiderosis) in patients aged 2 years and above chronic iron overload in patients with non-transfusion dependent thalassemia (NTDT) syndromes aged 10 years and older HOW ASUNRA 400MG TABLET WORKSASUNRA 400MG TABLET works by trapping and removing excess iron from the body, which is then excreted mainly in the form of stools and reduces the risk of organ damage to the liver and heart. As a result, ASUNRA 400MG TABLET helps to remove excess iron from the body. DIRECTIONS FOR USETake ASUNRA 400MG TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your physician will decide the correct dose and duration for you depending upon your age, body weight, and disease condition. SIDE EFFECTS OF ASUNRA 400MG TABLETCOMMON nausea, vomiting diarrhoea abdominal pain bloating constipation indigestion rash headache itching UNCOMMON dizziness fever, sore throat swelling of the arms or legs change in the skin’s colour anxiety sleep disorder tiredness Stop taking ASUNRA 400MG TABLET and contact your physician immediately if you experience any of the following side effects: severe allergic reactions such as rash, red skin, blistering of the lips, eyes or mouth, skin peeling, high fever, flu-like symptoms, enlarged lymph nodes rash, swelling of the face, throat causing difficulty breathing and dizziness decrease in urine output signs of liver problems such as drowsiness, upper right abdominal pain, yellowish discolouration of skin or whites of the eye (jaundice) and dark urine signs of a high level of ammonia in your blood, such as difficulty thinking or remembering information, solving problems, being less alert, aware, or feeling very sleepy with low energy, which may be associated with liver or renal problems and lead to a change in brain function vomiting blood and/or black-coloured stools severe abdominal pain frequent heartburn partial loss of vision severe upper stomach pain (pancreatitis) blurred or cloudy eyesight reduced hearing
Warnings & Precautions
& PRECAUTIONSPREGNANCYMonitoring requiredASUNRA 400MG TABLET is generally not recommended for use in pregnant women unless considered necessary. Contact your doctor before taking ASUNRA 400MG TABLET. BREASTFEEDINGContraindicatedASUNRA 400MG TABLET is generally not recommended for use in breastfeeding women as it may pass through the breast milk unless considered necessary. Contact your doctor before taking ASUNRA 400MG TABLET. DRIVING AND USING MACHINESUse with CautionDo not drive or operate any machines if you feel dizziness, after taking ASUNRA 400MG TABLET. KIDNEYConsult your doctorASUNRA 400MG TABLET is not recommended for use in patients with moderate to severe kidney disease and should be used with caution in patients with decreased urine output. Contact your doctor before taking ASUNRA 400MG TABLET. LIVERContraindicatedASUNRA 400MG TABLET is not recommended for use in patients with severe liver disease. Contact your doctor before taking ASUNRA 400MG TABLET. ALLERGYContraindicatedDo not take ASUNRA 400MG TABLET if you are allergic to Deferasirox or to other ingredients in this medicine. HEART DISEASEUse with CautionASUNRA 400MG TABLET should be used with caution in patients with heart diseases due to iron overload. Contact your doctor before taking ASUNRA 400MG TABLET. USE IN PEDIATRICSConsult your doctorASUNRA 400MG TABLET is not recommended for use in children under 2 years of age. It should be used with caution in children (above 2 years of age) and adolescents, who receive or do not receive blood transfusions. Contact your doctor before taking ASUNRA 400MG TABLET. USE IN GERIATRICSUse with CautionASUNRA 400MG TABLET should be used with caution in elderly patients aged 65 years or above. Contact your doctor before taking ASUNRA 400MG TABLET. OTHERSASUNRA 400MG TABLET is not recommended for use if you have: advanced stage of myelodysplastic syndrome (decreased production of blood cells by the bone marrow) have advanced stage of cancer poor performance status severe thrombocytopenia Before taking ASUNRA 400MG TABLET inform your doctor if you have: low levels of white blood cells, worsening anaemia, pancytopenia, or bone marrow failure blurred vision, decreased hearing diarrhoea, vomiting gastrointestinal ulcers or haemorrhages
Drug Interactions
SA. Drug-Drug interactions: Before taking ASUNRA 400MG TABLET inform your doctor if you are taking any of the following medicine: iron chelators ex. deferiprone (medicines used in iron overload) aluminium-containing antacids (medicines used to manage heartburn) cyclosporin (used for the rejection of the transplanted organ and manages other conditions, such as rheumatoid arthritis or atopic dermatitis) painkillers or anti-inflammatory medicines (ex. aspirin, ibuprofen, corticosteroids like fluticasone) oral bisphosphonates (medicines used to manage osteoporosis) warfarin (medicines used to manage blood clots) hormonal contraceptive agents (medicines used for pregnancy) bepridil (medicines used to manage heart problems) eletriptan, dihydroergotamine, ergotamine (medicines used for migraines) repaglinide (used to manage diabetes) rifampicin (used to manage tuberculosis) phenytoin, phenobarbital, carbamazepine (used to manage epilepsy) paclitaxel (medicines used for cancer) theophylline (used to manage asthma) tizanidine (medicines used to relax muscle) bile acid sequestrants like cholestyramine, colesevelam, colestipol) (medicines used to lower cholesterol levels) busulfan (used in bone marrow transplantation) midazolam (medicines used for anxiety and insomnia) alfentanil (medicines used in anaesthesia) aprepitant (medicines used for nausea and vomiting after chemotherapy) budesonide (medicines used to manage asthma) buspirone (medicines used to manage anxiety) conivaptan, tolvaptan (medicines used for low sodium levels) darifenacin (medicines used to manage overactive bladder) darunavir, ritonavir, indinavir, lopinavir, maraviroc, saquinavir, tipranavir (medicines used to manage HIV infection) dasatinib (used for chronic myeloid leukaemia) dronedarone, quinidine (medicines used to manage heart rhythm disorders) eplerenone (medicines used to manage heart failure) everolimus, sirolimus, tacrolimus (medicines used for rejection of transplant organ) felodipine, nisoldipine (medicines used to manage high blood pressure) fentanyl (medicines used to relieve severe pain) lovastatin, simvastatin (medicines used to lower cholesterol levels) lurasidone, quetiapine, clozapine (medicines used to manage manage schizophrenia) pimozide (used for motor or verbal tics) sildenafil, vardenafil (medicines used for erectile dysfunction) triazolam (medicines used to manage insomnia) ticagrelor (medicines used to manage blood clots) alosetron (medicines used to manage irritable bowel syndrome) caffeine (medicines used to manage wakefulness, headache, migraine) duloxetine (a medicine used to manage depression) melatonin, ramelteon (medicines used for sleep problems) tacrine (medicines used for alzheimer’s disease) Overdosage: If you or anyone else accidentally have taken too much of ASUNRA 400MG TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdosage are nausea, vomiting, abdominal pain, diarrhoea, and kidney or liver problems. SYNOPSIS Drug : Deferasirox Pharmacological Category : Iron Chelators Therapeutic Indication : Chronic Iron overload Dosage Forms : Tablet MORE INFORMATION Keep ASUNRA 400MG TABLET out of the sight and reach of children Store ASUNRA 400MG TABLET below 30°C
Frequently Asked Questions
Common questions and answers about Asunra 400mg Tablet 6'S.
How does ASUNRA 400MG TABLET work?
ASUNRA 400MG TABLET works by trapping and removing excess iron from the body, which is then excreted mainly in the form of stools and reduces the risk of organ damage to the liver and heart.
What are the side effects of taking ASUNRA 400MG TABLET?
The most common side effects of taking ASUNRA 400MG TABLET are nausea, vomiting, diarrhoea, abdominal pain, bloating, constipation, indigestion, rash, itching, headache, and change in liver or kidney function tests or urine tests. Contact your physician if any of the side effects worsen.
Who should not take ASUNRA 400MG TABLET?
ASUNRA 400MG TABLET should not be used if you are allergic to this medicine or by pregnant or breastfeeding women, people with severe liver disease, moderate to severe kidney disease, advanced stage myelodysplastic syndrome, advanced cancer, poor performance status, or severe thrombocytopenia. Contact your doctor before taking ASUNRA 400MG TABLET.
Does ASUNRA 400MG TABLET cause liver damage?
Yes. ASUNRA 400MG TABLET may cause liver damage. If you experience any unusual symptoms such as drowsiness, upper right abdominal pain, yellowish discoloration of the skin or whites of the eyes (jaundice), or dark urine, stop taking ASUNRA 400MG TABLET and contact your doctor.
Does ASUNRA 400MG TABLET cause vision loss?
Yes. ASUNRA 400MG TABLET may cause partial vision loss. Stop taking ASUNRA 400MG TABLET and contact your doctor if you experience any unusual symptoms like blurred or cloudy eyes.
Article Information
Written By
DETAILSWritten By Dr. Janet.C, Pharm.D
Medical Content Writer
Last Updated
24 Feb 2024