APREZO 10 Tablet 4's
Key Information
Generic Name
Generic Name Apremilast 10 mg
Manufacturer
Glenmark Pharmaceuticals Ltd
Variant
4 Tablet(s) in a Strip
Country of Origin
India
Detailed Information
Introduction
APREZO 10 TABLET contains Apremilast which belongs to a group of medicines called Phosphodiesterase 4 inhibitors. APREZO 10 TABLET is used to manage active psoriatic arthritis (chronic inflammatory disease of joints) in adults when disease-modifying antirheumatic drugs (medications used to manage arthritis) are insufficient to manage the disease. APREZO 10 TABLET is also used to manage moderate to severe chronic plaque psoriasis (chronic inflammatory skin disease) when phototherapy (management with a special type of light), and/or systemic therapy (with ciclosporin, methotrexate, psoralen) are insufficient to manage the disease. The medicine is also indicated for use to manage Behçet’s disease (rare inflammatory disorder that affects blood vessels and tissues) in adults. APREZO 10 TABLET is not recommended for use in patients allergic to Apremilast. Before taking APREZO 10 TABLET, inform your doctor if you are underweight, and/or have gut problems, intolerance to certain sugars (such as lactose), kidney problems (such as severe kidney disease), and/or liver problems (such as hepatic impairment). APREZO 10 TABLET is generally not recommended for use during pregnancy and in women planning for pregnancy. It is also not recommended for use in breastfeeding women as it is not known whether the medicine passes through breastmilk. APREZO 10 TABLET is generally not recommended for use in children and adolescents (aged below 18 years) and is advised to be used with caution in elderly patients (aged 65 years/above) after consulting the doctor. The most common
Uses
OF APREZO 10 TABLETIn adults: Manage active psoriatic arthritis when disease-modifying antirheumatic drugs are insufficient to manage the disease Manage moderate to severe chronic plaque psoriasis (chronic inflammatory skin disease) when phototherapy (management with a special type of light), and/or systemic therapy (with ciclosporin, methotrexate, psoralen) are insufficient to manage the disease Manage Behçet’s disease (rare inflammatory disorder that affects blood vessels and tissues)
How It Works
APREZO 10 TABLET works by reducing the activity of phosphodiesterase 4 (enzyme involved in the process of inflammation) which leads to reduced occurrence of inflammatory process and providing relief from signs & symptoms associated with conditions such as psoriatic arthritis, chronic plaque psoriasis and Behcet’s disease in affected individuals.
Directions for Use
Take APREZO 10 TABLET as advised by your physician. Swallow the medicines with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
Side Effects
taking APREZO 10 TABLET are stomach pain, loss of appetite, indigestion/heartburn, diarrhoea, nausea, vomiting, and/or headache. Consult your doctor if any of these side effects worsens. USES OF APREZO 10 TABLETIn adults: Manage active psoriatic arthritis when disease-modifying antirheumatic drugs are insufficient to manage the disease Manage moderate to severe chronic plaque psoriasis (chronic inflammatory skin disease) when phototherapy (management with a special type of light), and/or systemic therapy (with ciclosporin, methotrexate, psoralen) are insufficient to manage the disease Manage Behçet’s disease (rare inflammatory disorder that affects blood vessels and tissues) HOW APREZO 10 TABLET WORKSAPREZO 10 TABLET works by reducing the activity of phosphodiesterase 4 (enzyme involved in the process of inflammation) which leads to reduced occurrence of inflammatory process and providing relief from signs & symptoms associated with conditions such as psoriatic arthritis, chronic plaque psoriasis and Behcet’s disease in affected individuals. DIRECTIONS FOR USETake APREZO 10 TABLET as advised by your physician. Swallow the medicines with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition. SIDE EFFECTS OF APREZO 10 TABLETCOMMON stomach pain, loss of appetite, frequent bowel movements, indigestion/heartburn diarrhoea, nausea, vomiting headache, back pain, tiredness upper respiratory tract infections such as common cold, cough, runny nose, sinus infection difficulty in sleeping (insomnia) bronchitis (inflammation and swelling of tubes in lungs) depression migraine UNCOMMON rash, red itchy welts weight loss allergic reaction bleeding in the bowel/stomach suicidal ideation/behaviour RAREStop taking APREZO 10 TABLET and contact your doctor immediately if you experience any of the following side effects: changes in behaviour/mood, feeling depressed, suicidal thoughts/behaviour
Warnings & Precautions
& PRECAUTIONSPREGNANCYAPREZO 10 TABLET is generally not recommended for use during pregnancy and in women planning for pregnancy. Consult your doctor before taking the medicine. BREASTFEEDINGAPREZO 10 TABLET is generally not recommended for use in breastfeeding women since it is not known whether the medicine passes through breast milk. Consult your doctor before taking the medicine. DRIVING AND USING MACHINESAPREZO 10 TABLET is unlikely to affect your ability to drive or operate machines. KIDNEYAPREZO 10 TABLET should be taken with caution in patients with severe kidney problems. Consult your doctor before taking APREZO 10 TABLET. LIVERAPREZO 10 TABLET should be used with caution in patients with liver problems such as hepatic impairment. Consult your doctor before taking APREZO 10 TABLET. ALLERGYDo not take APREZO 10 TABLET if you are allergic to Apremilast, and/or any of the other ingredients of this medicine. OTHERSBefore taking APREZO 10 TABLET, inform your doctor if you: are underweight suffer from any gut problems have intolerance to certain sugars (such as lactose) Use in Paediatrics: APREZO 10 TABLET is generally not recommended for use in children and adolescents (aged below 17 years). Consult your doctor before taking APREZO 10 TABLET. Use in Geriatrics: APREZO 10 TABLET should be used with caution in elderly patients (aged above 65 years). Consult your doctor before taking APREZO 10 TABLET.
Drug Interactions
SA. Drug-Drug interactions: Before taking APREZO 10 TABLET, inform your doctor if you are taking any of the following medicine: rifampicin (medicines used to manage tuberculosis) phenytoin, phenobarbital, carbamazepine (medicines used to manage seizures/epilepsy) St John’s Wort (herbal medicine used for mild anxiety and depression) Overdosage: If you or anyone else accidentally take too much of APREZO 10 TABLET, consult your doctor immediately or visit the nearby hospital. SYNOPSIS Drug : Apremilast Pharmacological Category : Phosphodiesterase - 4 inhibitors Therapeutic Indication : Psoriatic arthritis, Plaque psoriasis, Behcet’s disease Dosage Forms : Tablet MORE INFORMATION Keep APREZO 10 TABLET out of the sight and reach of children Do not store APREZO 10 TABLET above 30°C
Article Information
Written By
DETAILS Written By Dr. K .AZEEM HUSSAIN
Medical Content Writer
Reviewed By
Dr. Sankara Babu Gorle
Medical Expert
Last Updated
29 Nov 2022