Amlodac D Tablet 10'S

Hypertension (3051)Rx required

Key Information

Generic Name

Generic Name Amlodipine 5 mg+Indapamide 1.5 mg

Manufacturer

Zydus Healthcare Ltd

Variant

10 Tablet(s) in a Strip

Country of Origin

India

Detailed Information

Introduction

AMLODAC D TABLET is a combination of Amlodipine and Indapamide, which belong to the group of medicines called Calcium-channel blockers and Thiazide diuretics. It is used in the management of high blood pressure (hypertension), which is a condition in which the force of the blood is consistently high against the walls of the arteries, which can increase the risk of heart disease, kidney disease and stroke. Inform your doctor if you are pregnant or breastfeeding before taking this medicine. Inform your doctor if you have any problems related to the kidney, liver or heart. If you are elderly and younger than 18 years old, you should consult with a doctor before taking the medicine. Before taking AMLODAC D TABLET, inform your doctor if you have any conditions such as diabetes, low blood pressure, gout, low levels of potassium in the blood (hypokalaemia) and symptoms of fluid accumulation around the eye that present with visual disturbances or eye pain. The most common

Uses

OF AMLODAC D TABLET Manage hypertension (high blood pressure)

How It Works

AMLODAC D TABLET helps to reduce high blood pressure, where amlodipine works by inhibiting the movement of calcium ions into both vascular smooth muscle and cardiac muscle, resulting in lower blood pressure by relaxing the blood vessels and improving the flow of blood to the heart muscles. Indapamide reduces blood pressure by promoting the excretion of extra fluid and certain salts (sodium) from the body by increasing the amount of urine produced by the kidneys.

Directions for Use

Always take AMLODAC D TABLET as instructed by your doctor. Take AMLODAC D TABLET with or without food, swallow the medicine as a whole and do not crush or chew the medicine. Do not stop taking the medicine without informing your doctor.

Side Effects

taking AMLODAC D TABLET are headache, nausea, dizziness and tiredness. USES OF AMLODAC D TABLET Manage hypertension (high blood pressure) HOW AMLODAC D TABLET WORKSAMLODAC D TABLET helps to reduce high blood pressure, where amlodipine works by inhibiting the movement of calcium ions into both vascular smooth muscle and cardiac muscle, resulting in lower blood pressure by relaxing the blood vessels and improving the flow of blood to the heart muscles. Indapamide reduces blood pressure by promoting the excretion of extra fluid and certain salts (sodium) from the body by increasing the amount of urine produced by the kidneys. DIRECTIONS FOR USEAlways take AMLODAC D TABLET as instructed by your doctor. Take AMLODAC D TABLET with or without food, swallow the medicine as a whole and do not crush or chew the medicine. Do not stop taking the medicine without informing your doctor. SIDE EFFECTS OF AMLODAC D TABLETCOMMON headache dizziness nausea stomach pain visual disturbances muscle cramps diarrhea constipation indigestion increased heart rate flushing (skin redness) weakness, tiredness oedema (fluid retention) reduced levels of potassium in the blood red raised rashes on the skin UNCOMMON altered taste sensation mood changes, depression enlargement of breasts in men (gynecomastia) tingling or numbness sensation in arms or leg ringing sensation in the ear low blood pressure cough, breathing difficulties dry mouth increase or decrease in weight impotence (unable to achieve erection) urine urgency vomiting reduced levels of sodium in the blood (hyponatremia) purple spots on the skin RARE confusion low levels of chloride or magnesium in the blood Stop taking this medicine and contact your doctor immediately if you experience any of the following side effects: severe skin reactions such as stevens-johnson syndrome, toxic epidermal necrolysis (skin rash, itching, blistering reddening of skin all over the body, peeling and swelling of the skin, swelling of the mucous membrane) heart attack or irregular heartbeat signs of an inflamed pancreas (severe stomach and back pain, usually feeling unwell) sudden chest pain, wheezing and trouble breathing angioedema or urticaria (such as rash, swelling of the face, lips, mouth, throat or airways which can lead to difficulty in breathing or swallowing)

Warnings & Precautions

& PRECAUTIONSPREGNANCYAMLODAC D TABLET should not be used by pregnant women. Consult with your doctor for advice before taking the medicine. BREASTFEEDINGAMLODAC D TABLET is not recommended for use by breastfeeding women. Consult with your doctor for advice before taking the medicine. DRIVING AND USING MACHINESAMLODAC D TABLET may cause side effects such as dizziness or tiredness due to low blood pressure, so use caution while driving or operating heavy machinery. ALCOHOLConsumption of alcohol is not recommended during management with AMLODAC D TABLET. KIDNEYAMLODAC D TABLET should be used with caution in patients with kidney disease undergoing dialysis and it is not recommended for use in patients with severe kidney disease. Consult with your doctor for advice before taking AMLODAC D TABLET. LIVERAMLODAC D TABLET should be used with caution in liver disease patients and it is not recommended for use in patients with severe liver disease. Consult with your doctor for advice before taking AMLODAC D TABLET. ALLERGYDo not take this medicine if you are allergic to Amlodipine and Perindopril or other inactive preparations of this medicine. HEART DISEASEAMLODAC D TABLET should not be used in patients with heart problems such as heart failure, recent heart attack, narrowing of the aortic heart valve (aortic stenosis) or cardiogenic shock (where the heart is unable to pump a sufficient amount of blood to the body). OTHERSDo not take AMLODAC D TABLET, if you have: hepatic encephalopathy severe low blood pressure Before taking AMLODAC D TABLET, inform your doctor if you have: severe increase in blood pressure diabetes gout (joint pain and swelling) allergic problems with natural sunlight or UV rays (photosensitivity reactions) symptoms of fluid accumulation in the vascular layer of the eye (choroidal effusion) or increase in eye pressure such as eye pain or low eye vision Use in Pediatrics: AMLODAC D TABLET is not recommended for use in children under 18 years of age. Consult your doctor for advice. Use in Geriatrics: AMLODAC D TABLET should be used with caution in elderly patients and the dose may be adjusted according to age and weight. The management should be initiated based on kidney, liver or heart function.

Drug Interactions

SA. Drug-Drug interactions: Inform your doctor, if you are taking any of the following medicines ketoconazole, itraconazole, amphotericin B (used to manage fungal infections) verapamil, diltiazem (used to manage low blood pressure) phenobarbital, phenytoin, carbamazepine (used to manage seizures) erythromycin, clarithromycin, rifampicin (used to manage bacterial infections) nefazodone (used to manage depression) dantrolene infusion (used to manage body temperature abnormalities) tacrolimus (used to alter the immune system response) simvastatin (used to manage high cholesterol) St. john’s wort (herbal preparation used to manage depression) ritonavir, nelfinavir, indinavir (used to manage HIV) sildenafil (used to manage impotence) metformin (used to manage diabetes) allopurinol (used to manage gout) quinidine, amiodarone, hydroquinidine (used to manage heart rhythm disorder) bepridil (used to manage chest pain) diphemanil, cisapride (used to manage stomach ulcers) pentamidine (used to manage malaria) halofantrine (manages certain types of malaria) ibuprofen (used to manage swelling and pain) calcium supplements potassium-sparing diuretics such as spironolactone and amiloride (used to manage high blood pressure or heart failure) B. Drug-Food interactions: Do not eat grapefruit or drink grapefruit juice while taking this medicine as it increases the level of this medicine in the blood, resulting in blood pressure-lowering effects. Consult your doctor before taking AMLODAC D TABLET. Overdosage: If you or anyone else accidentally takes too much of AMLODAC D TABLET, consult your doctor immediately. Overdosage may cause side effects such as dizziness, light-headedness, nausea, cramps, flushing (redness of the skin), fainting, low blood pressure, urinary problems, drowsiness and confusion. SYNOPSIS Drug : Amlodipine, Indapamide Pharmacological Category : Calcium-channel blockers and Thiazide diuretics Therapeutic Indication : Hypertension Dosage Forms : Tablet MORE INFORMATION Keep AMLODAC D TABLET medicine out of reach from children Store at normal room temperature below 25°C

Article Information

I(

Written By

ity (HPRA). [Revised in February 2019] [Accessed 24th March 2022] https://www.hpra.ie/img/uploaded/swedocuments/9489d761-46b7-4af5-b8d9-d00564ccea84.pdf 8. Pfizer Labs. Food & Drug Administration. [Revised in May 2011] [Accessed 24th March 2022] https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/019787s047lbl.pdf USEFUL DIAGNOSTIC TESTS Kidney Function Test AUTHOR DETAILS Written By Dr. Dhivakaran R

Medical Content Writer

DS

Reviewed By

Dr. Sankara Babu Gorle

Medical Expert

Last Updated

17 Dec 2022

Tags

#hypertension (3051)#generic name amlodipine 5 mg+indapamide 1.5 mg