Amiur H 2.5/25mg Tablet 10'S
Key Information
Generic Name
Generic Name Amiloride 2.5 mg+Hydrochlorothiazide 25 mg
Manufacturer
East West Pharma
Variant
10 Tablet(s) in a Strip
Country of Origin
India
Detailed Information
Introduction
AMIUR H 2.5/25MG TABLET is a combination of Amiloride and Hydrochlorothiazide, which belongs to the group of medicines called Potassium-sparing and Thiazide diuretics. It is used to lower blood pressure in hypertensive (high blood pressure) patients. Hypertension is a condition when the blood flows at high pressure in
Uses
OF AMIUR H 2.5/25MG TABLET Manage hypertension Maintenance therapy for hepatic cirrhosis with ascites and oedema, congestive heart disease and fluid retention.
How It Works
AMIUR H 2.5/25MG TABLET is a combination of amiloride and hydrochlorothiazide. Amiloride works by acting in tubules in the kidney and promoting the excretion of sodium and water from the body without losing potassium. Hydrochlorothiazide also works by acting in the kidney tubules and promoting the excretion of water and potassium from the body by managing the reabsorption of the water. As a result, it controls blood pressure and fluid buildup in the body.
Directions for Use
Take AMIUR H 2.5/25MG TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew AMIUR H 2.5/25MG TABLET. Your doctor will determine the correct dose, frequency and duration of the management for you depending on your age, body weight and disease condition.
Side Effects
the symptoms get worse or persist. USES OF AMIUR H 2.5/25MG TABLET Manage hypertension Maintenance therapy for hepatic cirrhosis with ascites and oedema, congestive heart disease and fluid retention. HOW AMIUR H 2.5/25MG TABLET WORKSAMIUR H 2.5/25MG TABLET is a combination of amiloride and hydrochlorothiazide. Amiloride works by acting in tubules in the kidney and promoting the excretion of sodium and water from the body without losing potassium. Hydrochlorothiazide also works by acting in the kidney tubules and promoting the excretion of water and potassium from the body by managing the reabsorption of the water. As a result, it controls blood pressure and fluid buildup in the body. DIRECTIONS FOR USETake AMIUR H 2.5/25MG TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew AMIUR H 2.5/25MG TABLET. Your doctor will determine the correct dose, frequency and duration of the management for you depending on your age, body weight and disease condition. SIDE EFFECTS OF AMIUR H 2.5/25MG TABLETCOMMON nausea anorexia headache weakness dizziness rash UNCOMMON diarrhoea stomach pain gastrointestinal pain arrhythmia leg pain tiredness itching sensation shortness of breath RARE constipation, flatulence, GI disturbance bleeding in the intestine, fullness, anorexia hiccups, thirst, feeling unwell (malaise) vomiting, bad taste, dehydration vertigo (spinning sensation), stupor (feeling unconscious), sleepiness numbness, chest pain insomnia, visual disturbance nervousness, depression, mental confusion tachycardia, angina pectoris, digitalis toxicity orthostatic hypotension (a form of low blood pressure) muscle cramps/spasms joint pain, back pain, gout nasal congestion, flushing impotence difficult to urinate nocturia (frequent urination at night) incontinence (lack of control in urination and defecation) Stop taking AMIUR H 2.5/25MG TABLET and consult your doctor immediately if you experience any of the following side effects cardiovascular: vasculitis (inflammation of the blood vessels), cutaneous vasculitis (inflammation on the walls of blood vessels) gastrointestinal: abnormal liver function, jaundice (intrahepatic cholestatic jaundice (type of jaundice)), activation of pre-existing peptic ulcer, cramping, gastric irritation, pancreatitis (inflammation of the pancreas), dry mouth, sialadenitis (inflammation of the salivary gland) endocrine: glycosuria (excess sugar in the urine), hyperglycaemia (high glucose level), hyperuricemia (high uric level) hypersensitivity: urticaria (itchy rash), serious allergic reactions respiratory: respiratory distress including pneumonitis (inflammation of lung tissue) special senses: sensitivity to light, blurred vision
Warnings & Precautions
& PRECAUTIONSPREGNANCYAMIUR H 2.5/25MG TABLET is not recommended during pregnancy, as it may harm the developing baby. Consult your doctor before taking AMIUR H 2.5/25MG TABLET. BREASTFEEDINGAMIUR H 2.5/25MG TABLET is not recommended for use by breastfeeding mothers, as the medicine can pass through breastmilk and harm breastfed babies. Consult your doctor before taking AMIUR H 2.5/25MG TABLET. DRIVING AND USING MACHINESDo not drive or operate heavy machines if you feel weak, tired, dizzy, dazed or vertigo (spinning sensation of your head) after taking AMIUR H 2.5/25MG TABLET. ALCOHOLAvoid consuming alcohol while taking AMIUR H 2.5/25MG TABLET, as it can cause dizziness or fainting when standing up from a resting position. KIDNEYAMIUR H 2.5/25MG TABLET is not recommended for use in patients with severe kidney disease or other kidney problems such as anuria (failure of the kidneys to produce urine) and kidney failure and must be used with caution in patients suffering from abnormally high levels of blood urea and nitrogen (azotaemia). Consult your doctor for advice before taking AMIUR H 2.5/25MG TABLET. LIVERAMIUR H 2.5/25MG TABLET is not recommended for use in patients suffering from severe liver failure or severe liver diseases such as hepatic cirrhosis and must be used with caution in patients suffering from liver problems or liver disease. Consult your doctor before taking AMIUR H 2.5/25MG TABLET. ALLERGYDo not take this medicine if you are allergic (hypersensitive) to amiloride, hydrochlorothiazide or other Sulphonamide-derived medicines. Talk to your doctor if you have a history of penicillin allergy as this medicine could increase the chance of causing fluid accumulation in your eyes. LUNGSAMIUR H 2.5/25MG TABLET should be used with caution in patients with breathing or lung problems (including inflammation or fluid in the lungs) following hydrochlorothiazide therapy in the past or a history of allergy associated with bronchial asthma. Consult a doctor for advice before taking AMIUR H 2.5/25MG TABLET. HEART DISEASEAMIUR H 2.5/25MG TABLET is not recommended in patients suffering from heart failure. Consult the doctor before taking AMIUR H 2.5/25MG TABLET. OTHERSAMIUR H 2.5/25MG TABLET is not recommended for use if you have: diabetes or diabetic neuropathy (nerve damage causing pain, weakness and numbness) increased potassium levels in the blood (hyperkalaemia) or taking potassium supplements or a potassium-rich diet Addison’s disease high levels of calcium in the blood (hypercalcaemia) Before taking AMIUR H 2.5/25MG TABLET, inform your doctor if you: have metabolic acidosis (increased acid levels in the blood than normal) have a high level of uric acid in the blood (hyperuricaemia) have pain and swelling in one or more joints (gout, a form of arthritis) have increased level of fats (cholesterol and triglyceride) in your blood have fluid and electrolyte imbalance [symptoms include dry mouth, weakness, lack of energy, drowsiness, restlessness, fits, confusion, muscle pain, cramps, low blood pressure (hypotension), decreased production of urine (oliguria), faster heartbeat (tachycardia), feeling sick (nausea) or being sick (vomiting). have or had skin cancer or if you develop an unexpected skin lesion are suffering from systemic lupus erythematosus (SLE) (an autoimmune disorder) are going to take tests for parathyroid function have a decrease in vision or eye pain due to fluid accumulation in the vascular layer of the eye (choroidal effusion) or an increase in pressure to your eye Use in Pediatrics: AMIUR H 2.5/25MG TABLET is not recommended for use in adolescents and children (below 18 years of age). Consult your doctor before taking AMIUR H 2.5/25MG TABLET. Use in Geriatrics: AMIUR H 2.5/25MG TABLET should be used with caution in elderly patients, especially if they are having high potassium levels, are diabetic or suffer from liver or heart failure. Consult your doctor before taking AMIUR H 2.5/25MG TABLET.
Drug Interactions
SA. Drug-Drug interactions: Before taking AMIUR H 2.5/25MG TABLET, inform your doctor if you are taking any of the following medicine: medicines used to increase urination (Ex. spironolactone, triamterene), potassium supplements (Ex. Kay Ciel) medicines used to manage mood disorders (anti−psychotic) (Ex. lithium) medicines used to manage diabetes (Ex. insulin, chlorpropamide) medicines used to manage certain rheumatic disorders (Ex. aspirin or ibuprofen) medicines used for organ transplant (immunosuppressants) (Ex. ciclosporin, tacrolimus) medicines used to manage Cushing’s syndrome (Ex. trilostane) medicines used to manage high blood pressure (ACE inhibitors) (Ex. enalapril) other medicines used to manage high blood pressure (angiotensin II antagonists) (Ex. losartan) medicines used to lower cholesterol (Ex. cholestyramine, colestipol) medicines used to reduce inflammation (corticosteroids) (Ex. prednisolone) corticotropin (Adrenocorticotropic Hormone - ACTH) medicines used to manage serious allergic reactions (adrenaline) (Ex. epinephrine) medicines used as a muscle relaxant (Ex. tubocurarine) medicines used as a sedative for relaxation and sleep (barbiturates) (Ex. phenobarbital) medicine used to relieve severe pain (Narcotic analgesic) (Ex. morphine) B. Drug-Food interaction: Avoid AMIUR H 2.5/25MG TABLET if you have a wheat allergy (different from coeliac disease) as it may increase the risk of experiencing the side effects. Overdosage: If you or anyone else have accidentally taken too much of this medicine, consult your doctor immediately. Symptoms include breathing difficulties, dehydration and electrolyte imbalance such as abnormal potassium, chloride and sodium level, leading to tiredness, confusion, muscle twitching, fits and coma, etc. SYNOPSIS Drug : Amiloride and Hydrochlorothiazide Pharmacological Category : Thiazide-Diuretics and Potassium-sparing diuretics Therapeutic Indication : Lower blood pressure, manage heart failure and hepatic cirrhosis, manage fluid retention Dosage Forms : Tablet MORE INFORMATION Keep out of reach from children Store at room temperature
Article Information
Written By
DETAILS Written By Dr. Dhivakaran R
Medical Content Writer
Reviewed By
Dr. Sankara Babu Gorle
Medical Expert
Last Updated
08 Dec 2022