Amifru 5/40mg Tablet 10'S
Key Information
Generic Name
Generic Name Amiloride 5 mg+Frusemide 40 mg
Manufacturer
Torrent Pharmaceuticals Ltd
Variant
10 Tablet(s) in a Strip
Country of Origin
India
Detailed Information
Introduction
AMIFRU 5/40MG TABLET is a combination of Amiloride and Furosemide which belongs to the group of medicines called Diuretics. It is used in the management of extra build-up of water in the body. Symptoms include swollen ankles, feeling more tired than usual and shortness of breath. AMIFRU 5/40MG TABLET is not recommended for use in patients with severe kidney and liver problems, low blood volume or dehydration problem, not passing any urine, addison’s disease (which makes you feel weak and tired). AMIFRU 5/40MG TABLET should be used with caution in patients with diabetes, low blood pressure, prostate problems, gout, systemic lupus erythematosus and if you are scheduled for a glucose test. AMIFRU 5/40MG TABLET is not recommended for use in pregnant and breastfeeding women. Also, it is not recommended for use in children and adolescents (below 18 years of age). It should be used with caution in elderly patients (aged 65 years and above) particularly those with dementia or other conditions which may increase the risk of low blood pressure. The most common
Uses
OF AMIFRU 5/40MG TABLET Manage extra build-up of water in the body
How It Works
AMIFRU 5/40MG TABLET effectively stops extra build-up of water in the body by acting on different parts of the kidney and promoting water excretion. It inhibits certain system (sodium-potassium-chloride cotransporters) which results in increased excretion of water with some salts. AMIFRU 5/40MG TABLET also has a potassium-sparring effect and reduces the amount of potassium excretion from the body.
Directions for Use
Take AMIFRU 5/40MG TABLET as advised by your doctor. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
Side Effects
taking AMIFRU 5/40MG TABLET are diarrhoea, constipation, loss of appetite, stomach pain, weakness and headache. Consult your doctor if any of the side effects worsen. USES OF AMIFRU 5/40MG TABLET Manage extra build-up of water in the body HOW AMIFRU 5/40MG TABLET WORKSAMIFRU 5/40MG TABLET effectively stops extra build-up of water in the body by acting on different parts of the kidney and promoting water excretion. It inhibits certain system (sodium-potassium-chloride cotransporters) which results in increased excretion of water with some salts. AMIFRU 5/40MG TABLET also has a potassium-sparring effect and reduces the amount of potassium excretion from the body. DIRECTIONS FOR USETake AMIFRU 5/40MG TABLET as advised by your doctor. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition. SIDE EFFECTS OF AMIFRU 5/40MG TABLETCOMMON muscle cramps weakness skin rash nausea, vomiting, stomach pain headache diarrhoea, constipation loss of appetite blurred vision numbness or tingling sensation UNCOMMON deafness RAREStop taking AMIFRU 5/40MG TABLET and contact your doctor immediately if you experience any of the following side effects: severe allergic reactions (signs include shock such as difficulty in breathing, cold clammy skin, pale skin colour and racing heartbeat) severe stomach or back pain (signs of pancreatitis) bruising more easily, getting more infections, feeling weak or tired more than usual dehydration or body chemical changes (signs include increased thirst, headache, feeling dizzy or light-headed, fainting, confusion, muscle or joint pains or weakness, cramps or spasms, stomach upsets or uneven heartbeats) signs of liver problems (yellowing of the skin or eyes and dark urine) and in severe cases it may cause liver encephalopathy symptoms to include forgetfulness, fits, mood changes and coma inflammation of the kidney (signs include swollen ankles or high blood pressure) stevens-johnson syndrome (signs include Blistering or peeling of the skin around the lips, eyes, mouth, nose and genitals, flu-like symptoms and fever) epidermal necrolysis (signs include skin layer may peel off to leave large areas of raw exposed skin all over the body) acute generalised exanthematous pustulosis (signs include skin becoming red with swollen areas covered in numerous small pustules) dizziness, fainting and loss of consciousness
Warnings & Precautions
& PRECAUTIONSPREGNANCYGBNKEYWORD] is not recommended for use in pregnant women. Consult your doctor for advice. AMIFRU 5/40MG TABLET is not recommended for use in breastfeeding women as it may pass through the breast milk. Consult your doctor for advice. BREASTFEEDINGAMIFRU 5/40MG TABLET is not recommended for use in breastfeeding women as it may pass through the breast milk. Consult your doctor for advice. DRIVING AND USING MACHINESDo not drive or operate any machines if you feel dizzy or unwell after taking AMIFRU 5/40MG TABLET. KIDNEYAMIFRU 5/40MG TABLET is not recommended for use in patients having severe kidney disease. It should be used with caution in patients with kidney problems. Consult your doctor before taking AMIFRU 5/40MG TABLET. LIVERAMIFRU 5/40MG TABLET is not recommended for use in patients having severe liver problems. It should be used with caution in patients with liver problems. Consult your doctor before taking AMIFRU 5/40MG TABLET. ALLERGYDo not take AMIFRU 5/40MG TABLET if you are allergic to Amiloride, Furosemide or sulphonamides such as sulfadiazine or co-trimoxazole. OTHERSAMIFRU 5/40MG TABLET is not recommended for use if you: have a low volume of blood are dehydrated are unable to pass urine have increased or decreased potassium or sodium levels in the blood have Addison’s disease Before taking AMIFRU 5/40MG TABLET, inform your doctor if you: have difficulty in passing urine have diabetes have low blood pressure or feel dizzy when standing up have gout have prostate problems are dizzy or dehydrated (due to water loss in the body) have systemic lupus erythematosus are going to have a glucose test Use in pediatrics: AMIFRU 5/40MG TABLET is not recommended for use in children and adolescents (aged less than 18 years). Consult your child’s doctor for advice. Use in geriatrics: AMIFRU 5/40MG TABLET should be used with caution in elderly patients (aged 65 years and above) particularly those with dementia or other conditions which may increase the risk of low blood pressure. Consult your doctor before taking AMIFRU 5/40MG TABLET.
Drug Interactions
SA. Drug – Drug Interactions: Before taking AMIFRU 5/40MG TABLET inform your doctor if you are taking any of the following medicines: medicines which change the amount of potassium in your blood (Ex. potassium chloride, triamterene) medicines used to manage high blood pressure or other heart problems (Ex. ramipril, enalapril, perindopril, losartan, digoxin, candesartan, irbesartan and bendroflumethiazide) medicines used to relax your muscles during surgery (Ex. propofol, ketamine) medicines used in the management of diabetes (Ex. metformin, sitagliptin) medicines used for wheezing or difficulty in breathing (Ex. theophylline), asthma (Ex. salbutamol, salmeterol, formoterol, bambuterol, terbutaline sulphate) medicines used the management of epilepsy (Ex. phenytoin, carbamazepine) medicines used to manage mental illness (Ex. lithium), manage depression (Ex. reboxetine) medicines used to manage some cancers (Ex. cisplatin, methotrexate), manage breast cancer (Ex. aminoglutethimide) medicines used for managing pain and inflammation such as NSAIDS (Ex. aspirin, ketoprofen, ibuprofen, indomethacin), corticosteroids (Ex. prednisolone) medicines used to stop the rejection of organs after a transplant (Ex. ciclosporin) medicines used for ulcers of the food pipe (Ex. carbenoxolone), ulcers of stomach (Ex. sucralfate) medicines used to manage fungal infections (Ex. amphotericin B) medicine used in cough medicines (Ex. liquorice) medicines used to gout (Ex. probenecid) medicines used to manage bacterial infections (Ex. gentamicin, amikacin, netilmicin, tobramycin, neomycin, vancomycin, cefixime, cefpodoxime) medicines used as injections before Xray examination (Ex. barium, iodine) medicines used for constipation (Ex. bisacodyl, senna) Overdosage: If you or anyone else accidentally take too much of AMIFRU 5/40MG TABLET, consult your doctor immediately or visit the nearby hospital. Overdose symptoms of AMIFRU 5/40MG TABLET includes dry mouth, feeling thirsty, muscle pain or cramps, nausea, vomiting, weak or uneven heartbeat, feeling dizzy, weak or sleepy. SYNOPSIS Drug : Amiloride, Furosemide Pharmacological Category : Potassium-sparing diuretic, Loop diuretic Therapeutic Indication : Stops extra build-up of water in the body Dosage Forms : Tablet MORE INFORMATION Keep AMIFRU 5/40MG TABLET out of reach of children Store AMIFRU 5/40MG TABLET at room temperature
Article Information
Written By
DETAILS Written By Dr. R. Dinesh John Rajkumar
Medical Content Writer
Reviewed By
Dr. Sankara Babu Gorle
Medical Expert
Last Updated
16 Dec 2022