Ambisome 50mg Injection 1'S
Key Information
Generic Name
Generic Name Amphotericin B 50 mg
Manufacturer
Viatris
Country of Origin
United States
Detailed Information
Introduction
INTRODUCTION ABOUT AMBISOME 50MG INJECTIONAMBISOME 50MG INJECTION contains Amphotericin B which belongs to the group of medicines called Anti-fungal agents. AMBISOME 50MG INJECTION is used to manage invasive fungal infections in patients who are resistant/intolerant to conventional Amphotericin B therapy. AMBISOME 50MG INJECTION is not recommended for use in patients allergic to Amphotericin B. It is also not recommended for use in patients with common/superficial, clinically inapparent fungal infections (which are detectable only by positive skin/serologic tests). Before receiving AMBISOME 50MG INJECTION, inform your doctor if you are neutropenic, and/or have liver problems (such as hepatic impairment), and suffer from kidney problems/undergoing dialysis. AMBISOME 50MG INJECTION should be used with caution in pregnant and breast-feeding women only if it is clearly necessary. It is also used with caution in children and adolescents (aged below 18 years) and in elders (aged above 65 years) after consulting with the doctor. The most common
Uses
OF AMBISOME 50MG INJECTION Manage invasive fungal infections in patients who are resistant/intolerant to conventional Amphotericin B therapy
How It Works
AMBISOME 50MG INJECTION binds to ergosterol (steroid present on the cell membranes of fungi) which leads to the formation of pores and ion leakage on the cell membrane resulting in fungal cell death thus managing invasive fungal infections in affected individuals.
Directions for Use
AMBISOME 50MG INJECTION will be given to you only by a doctor or a nurse into a vein as an intravenous infusion. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
Side Effects
receiving AMBISOME 50MG INJECTION are fever, chills, and/or rigors. Consult your doctor if any of these symptoms worsen. USES OF AMBISOME 50MG INJECTION Manage invasive fungal infections in patients who are resistant/intolerant to conventional Amphotericin B therapy HOW AMBISOME 50MG INJECTION WORKSAMBISOME 50MG INJECTION binds to ergosterol (steroid present on the cell membranes of fungi) which leads to the formation of pores and ion leakage on the cell membrane resulting in fungal cell death thus managing invasive fungal infections in affected individuals. DIRECTIONS FOR USEAMBISOME 50MG INJECTION will be given to you only by a doctor or a nurse into a vein as an intravenous infusion. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition. SIDE EFFECTS OF AMBISOME 50MG INJECTIONCOMMON fever chills/rigors
Warnings & Precautions
& PRECAUTIONSPREGNANCYAMBISOME 50MG INJECTION should be administered with caution in pregnant women only if it is clearly necessary. Consult your doctor before receiving the medicine. BREASTFEEDINGAMBISOME 50MG INJECTION should be administered with caution in breastfeeding women only if it is clearly necessary. Consult your doctor before receiving the medicine. DRIVING AND USING MACHINESAMBISOME 50MG INJECTION is unlikely to affect your ability to drive/operate machines. Consult your doctor before receiving AMBISOME 50MG INJECTION. KIDNEYAMBISOME 50MG INJECTION should be administered with caution in patients with kidney disease and in patients who are under dialysis. Consult your doctor before receiving the medicine. LIVERAMBISOME 50MG INJECTION should be administered with caution in patients with hepatic impairment, and/or other liver disease. Consult your doctor before receiving AMBISOME 50MG INJECTION. ALLERGYDo not receive AMBISOME 50MG INJECTION if you are allergic to Amphotericin B, and/or any other ingredients of this medicine. OTHERSAMBISOME 50MG INJECTION is not recommended for use if you: have common/superficial, clinically inapparent fungal infections (which are detectable only by positive skin/serologic tests) Before receiving AMBISOME 50MG INJECTION, inform your doctor if you: suffer from neutropenia (condition marked by low count of neutrophils) Use in Pediatrics: AMBISOME 50MG INJECTION should be used with caution in children and adolescents (aged below 18 years). Consult your doctor before child receives the medicine. Use in Geriatrics: AMBISOME 50MG INJECTION should be used with caution in elderly patients (aged above 65 years). Consult your doctor before receiving AMBISOME 50MG INJECTION.
Drug Interactions
SA. Drug–Drug interactions: Before receiving AMBISOME 50MG INJECTION, inform your doctor if you are taking any of the following medicine: nephrotoxic drugs (medicines that can cause damage to the kidney) Ex. minoglycosides, cisplatin zidovudine (used to manage HIV) cyclosporin (used to manage transplanted organ rejection) Overdosage: AMBISOME 50MG INJECTION will be administered to you only by a doctor or a nurse in a hospital, and so it is unlikely to receive an overdose. However, consult your doctor or nurse if you experience any unusual symptoms. SYNOPSIS Drug : Amphotericin B Pharmacological Category : Anti-fungal agent Therapeutic Indication : Invasive fungal infection Dosage Forms : Injection, Infusion, Emulsion, Gel MORE INFORMATION Keep AMBISOME 50MG INJECTION out of reach of children Store AMBISOME 50MG INJECTION under refrigeration at 2°C to 8°C
Article Information
Written By
DETAILS Written By Dr. K .AZEEM HUSSAIN
Medical Content Writer
Reviewed By
Dr. Sankara Babu Gorle
Medical Expert
Last Updated
22 Nov 2022