Alrista SR Tablet 10'S

Neuropathic Pain (649)Rx required

Key Information

Generic Name

Generic Name Epalrestat 150 mg

Manufacturer

Macleods Pharmaceuticals Pvt Ltd

Variant

10 Tablet(s) in a Strip

Country of Origin

India

Detailed Information

Introduction

INTRODUCTIONALRISTA SR contains Epalrestat which belongs to the group of medicines called Aldose reductase inhibitors. It is used in the management of diabetic neuropathy. Diabetic neuropathy is a serious and common complication of type 1 and type 2 diabetes, which is a type of nerve damage that occurs due to long-term high blood sugar levels in diabetic patients that affects most often the legs and feet. It is generally characterized by symptoms such as numbness/reduced ability to feel pain or temperature changes, tingling/burning sensation, sharp pains/cramps, and muscle weakness. Epalrestat works by inhibiting an enzyme (aldose reductase) which converts glucose into sorbitol. In diabetics, there is an excess sorbitol production that gets deposited in nerves and other tissues, causing diabetic neuropathy. By inhibiting the enzyme, epalrestat delays sorbitol accumulation in nerves and other tissues thus delaying the progression and occurrence of diabetic neuropathy in affected individuals. During management with ALRISTA SR, your doctor will closely monitor you if you have diabetic peripheral neuropathy with irreversible organic changes. ALRISTA SR is not recommended for use in patients with allergic to Epalrestat. It should be used with caution in patients with diabetic peripheral neuropathy with irreversible organic changes. ALRISTA SR should be used with caution in pregnant women only if it is clearly advised by your doctor. It should be used with caution in breastfeeding women after consulting the doctor. The safety and effectiveness of ALRISTA SR have not been established in children and adolescents (under 18 years of age), so consult your doctor before taking it. The most common

Uses

OF ALRISTA SR To manage diabetic neuropathy

How It Works

ALRISTA SR works by inhibiting an enzyme (aldose reductase) which converts glucose into sorbitol. In diabetics, there is excess production of sorbitol that gets deposited in nerves and other tissues, causing diabetic neuropathy. Thus, by inhibiting the enzyme, ALRISTA SR delays sorbitol accumulation in nerves and other tissues thereby delaying the progression and occurrence of diabetic neuropathy in affected individuals.

Directions for Use

Take ALRISTA SR as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.

Side Effects

taking ALRISTA SR are elevated liver enzymes (signs are dark urine, tiredness, itching, jaundice, and loss of appetite), and/or gastrointestinal disorders such as nausea, vomiting. Contact your doctor if any of these symptoms worsen. USES OF ALRISTA SR To manage diabetic neuropathy HOW ALRISTA SR WORKSALRISTA SR works by inhibiting an enzyme (aldose reductase) which converts glucose into sorbitol. In diabetics, there is excess production of sorbitol that gets deposited in nerves and other tissues, causing diabetic neuropathy. Thus, by inhibiting the enzyme, ALRISTA SR delays sorbitol accumulation in nerves and other tissues thereby delaying the progression and occurrence of diabetic neuropathy in affected individuals. DIRECTIONS FOR USETake ALRISTA SR as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition. SIDE EFFECTS OF ALRISTA SRCOMMON signs of elevated liver enzymes such as dark urine, tiredness, itching, jaundice (yellowing of your skin or eyes), and loss of appetite gastrointestinal disorders such as nausea, vomiting

Warnings & Precautions

& PRECAUTIONSPREGNANCYALRISTA SR should be used with caution in pregnant women only if it is considered clearly necessary. Consult your doctor before taking it. BREASTFEEDINGALRISTA SR should be used with caution in breastfeeding women. Consult your doctor before taking it. KIDNEYALRISTA SR should be used with caution in patients with kidney problems such as renal impairment. Consult your doctor before taking ALRISTA SR. ALLERGYDo not take ALRISTA SR if you are allergic to Epalrestat or any of the other ingredients of this medicine. OTHERSBefore taking ALRISTA SR, inform your doctor if you: have diabetic peripheral neuropathy with irreversible organic changes Use in pediatrics: The safety and effectiveness of ALRISTA SR have not been established in children and adolescents (under 18 years of age). Consult child’s doctor for advice. Use in geriatrics: ALRISTA SR should be used with caution in elderly patients (aged above 70 years). Consult your doctor before taking ALRISTA SR.

Drug Interactions

SOverdosage: If you or anyone else accidentally take too much of ALRISTA SR, consult your doctor immediately or visit the nearby hospital. SYNOPSIS Drug : Epalrestat Pharmacological Category : Aldose reductase inhibitor Therapeutic Indication : Diabetic neuropathy Dosage Forms : Tablet MORE INFORMATION Keep ALRISTA SR out of reach of children Store at room temperature

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