Acitrom 0.5mg Tablet 10'S
Key Information
Generic Name
Generic Name Nicoumalone 0.5 mg Also Known As: Acenocoumarol
Manufacturer
Abbott Healthcare Pvt Ltd
Variant
10 Tablet(s) in a Strip
Country of Origin
India
Detailed Information
Introduction
ACITROM 0.5MG TABLET contains Nicoumalone which belongs to the group of medicines called Anti-coagulants. It is used to manage or prevent the formation of blood clots in the body. Blood clots (also known as thrombosis) are semi-solid masses of blood cells deposited within the blood vessels. It happens due to excessive clumping of platelets (blood cells) or other blood proteins within the blood vessels. As a result, it blocks them and reduce blood flow within them, leading to various complications such as deep vein thrombosis (blood clot in veins of legs), pulmonary embolism (blood clot in veins of lungs), heart attack, abnormal heart rate or stroke. ACITROM 0.5MG TABLET can also be used as an adjunct in the management of coronary occlusion (block in heart which reduces oxygen and blood supply leading to heart attack) and transient cerebral ischemic attacks (mini stroke, caused by blockage in the blood vessel supplying the brain). Nicoumalone is a blood thinning medication. It works by preventing the formation of blood clots within the blood vessels. It blocks the actions of certain blood proteins and enzymes that forms blood clots in the body. As a result, it reduces the risk of heart attack and other serious complications such as stroke, deep vein thrombosis or pulmonary embolism. ACITROM 0.5MG TABLET cannot not dissolve an existing blood clot, but it can prevent them from growing larger. During management with ACITROM 0.5MG TABLET, your doctor would regularly monitor your blood clotting time to avoid the risk of unwanted
Uses
OF ACITROM 0.5MG TABLET Used to manage the formation of blood clots
How It Works
ACITROM 0.5MG TABLET is a blood thinning medication. It works by preventing the formation of blood clots within the blood vessels. It blocks the actions of certain blood proteins and enzymes (such as vitamin k reductase, prothrombin, coagulation factors VII, IX, X and protein C) that forms blood clots in the body. As a result, it improves blood flow and oxygen supply through the blood vessels and reduce the symptoms of blood clotting disorders such as deep vein thrombosis, pulmonary embolism, heart attack, abnormal heart rate or stroke.
Directions for Use
Take ACITROM 0.5MG TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition.
Side Effects
bleeding at the time of childbirth. It should be used with caution in children and in elderly patients. The most common side effect of ACITROM 0.5MG TABLET is increased bleeding tendency (even after minor cuts or wounds). Consult your doctor if your bleeding becomes uncontrollable. USES OF ACITROM 0.5MG TABLET Used to manage the formation of blood clots HOW ACITROM 0.5MG TABLET WORKSACITROM 0.5MG TABLET is a blood thinning medication. It works by preventing the formation of blood clots within the blood vessels. It blocks the actions of certain blood proteins and enzymes (such as vitamin k reductase, prothrombin, coagulation factors VII, IX, X and protein C) that forms blood clots in the body. As a result, it improves blood flow and oxygen supply through the blood vessels and reduce the symptoms of blood clotting disorders such as deep vein thrombosis, pulmonary embolism, heart attack, abnormal heart rate or stroke. DIRECTIONS FOR USETake ACITROM 0.5MG TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition. SIDE EFFECTS OF ACITROM 0.5MG TABLETCOMMON Bleeding gums Heavy menstrual bleeding Unexplained bruising or nosebleeds Severe bleeding from minor cuts or wounds RARE Loss of appetite Vomiting, nausea Hair loss Stop taking ACITROM 0.5MG TABLET and contact your doctor immediately if you experience any of the following side effects: Signs of bleeding in the stomach (abdominal pain, vomiting blood, bloody or black tarry stools) Signs of bleeding in the urinary tract (backache, blood in urine) Signs of bleeding in the brain (dizziness, severe headache, weakness in one arm or leg) Signs of bleeding in the eyes (such as eye redness) Allergic reaction (such as skin rash, itching, inflammation with fever)
Warnings & Precautions
& PRECAUTIONSPREGNANCYContraindicatedACITROM 0.5MG TABLET is not recommended for use in pregnant women, as it may cause serious harm to the growing foetus. Consult your doctor for advice before taking. Women of childbearing potential should use suitable contraceptive method to avoid getting pregnant. BREASTFEEDINGMonitoring requiredACITROM 0.5MG TABLET is not recommended for use in breastfeeding women unless considered necessary by the physician. Therefore, consult your doctor for advice before taking. DRIVING AND USING MACHINESUse with CautionACITROM 0.5MG TABLET does not affect your ability to drive or operate heavy tools or machines. ALCOHOLConsult your doctorAvoid consumption of alcohol while taking ACITROM 0.5MG TABLET, as it may lead to unwanted side effects. KIDNEYConsult your doctorACITROM 0.5MG TABLET is not recommended for use in patients having severe kidney diseases. It should be used with caution in patients having other kidney problems. Therefore, consult your doctor for advice before taking. LIVERConsult your doctorACITROM 0.5MG TABLET is not recommended for use in patients having severe liver diseases. It should be used with caution in patients having other liver problems. Therefore, consult your doctor for advice before taking. ALLERGYContraindicatedDo not take ACITROM 0.5MG TABLET if you are allergic to Nicoumalone, warfarin or any ingredients of this medicine. HEART DISEASEConsult your doctorACITROM 0.5MG TABLET is not recommended for use in patients having severe high blood pressure. It should be used with caution in patients having heart failure. Therefore, consult your doctor for advice before taking. USE IN PEDIATRICSUse with CautionACITROM 0.5MG TABLET should be used in caution in children and adolescents below (18 years). Consult your doctor for advice before taking. USE IN GERIATRICSUse with CautionACITROM 0.5MG TABLET should be used with caution in elderly patients (aged above 65 years). Proper dose adjustments are required in such patients. Therefore, consult your doctor for advice before taking. OTHERSACITROM 0.5MG TABLET is not recommended for use if you: Have any mental illness such as schizophrenia or dementia Have a habit of drinking excessive alcohol (alcohol abuse) Have recently had or are going to have any major surgery on your spine, brain or eyes Have stroke caused due to brain haemorrhage (bleeding in the brain) Have stomach ulcer or bleeding from intestines Have blood in urine or in vomit Have any forms of bleeding disorders or unexplained bruising Are going to receive any injections in your muscles Before taking ACITROM 0.5MG TABLET, inform your doctor if you: Have cancer Have any signs of infection or inflammation in the body Have overactive thyroid Have ever had any stomach or intestinal ulcer Have any recent wound or injury Need any injections into spine or as part of a scan, x-ray or any dental surgeries Have anaemia (low RBC count in the blood) Had recently met with an accident
Drug Interactions
SA. Drug-Drug interactions: Other medicines used to prevent blood clots (Ex. heparin, dipyridamole, clopidogrel, ticlopidine, ateplase or reteplase) Medicines used to manage bacterial infections (Ex. clindamycin, clarithromycin, tetracyclines, neomycin, chloramphenicol, amoxicillin, sulfasalazine, clavulanic acid, cephalosporins, ciprofloxacin, norfloxacin and ofloxacin) Medicines used to manage anxiety or depression (Ex. viloxazine, citalopram, fluoxetine, sertraline, paroxetine, or St. John’s Wort) Rifampicin (used to manage tuberculosis) Medicines used to manage pain or fever (Ex. aspirin, paracetamol, tramadol, phenylbutazone, celecoxib) Allopurinol or sulfinpyrazone (used to manage gout) Immunosuppressants (medicines used to suppress immune function) Ex. methylprednisolone or prednisolone Anabolic steroids (medicines used to manage hormonal disorders). Ex nandrolone, oxandrolone Medicines used to manage irregular heartbeat (Ex. amiodarone and quinidine) Medicines used to manage diabetes (Ex. tolbutamide, chlorpropamide, glimepiride) Thyroid hormones (used to manage thyroid deficiency states) Ex. levothyroxine or dextrothyroxine Medicines used to manage stomach problems (Ex. cimetidine, ranitidine, omeprazole, cisapride) Medicines used to control blood cholesterol levels (Ex. atorvastatin, fluvastatin, simvastatin fenofibrate, gemfibrozil, or cholestyramine) Disulfiram (a medicine used to control alcohol abuse) Etacrynic acid (a medicine used to manage water retention or high blood pressure) Glucagon (a medicine used to manage low blood sugar levels) Medicines used to manage fungal infections (Ex. econazole, miconazole, ketoconazole, fluconazole or griseofulvin) Metronidazole (a medicine used to manage protozoal infections) Glucosamine (a medicine used to manage bone problems) Medicines used to manage cancer (Ex. 5-fluorouracil, azathioprine, aminoglutethimide, mercaptopurine, or tamoxifen) Medicines used to manage HIV infection (Ex. indinavir, ritonavir, nelfinavir or saquinavir) Oral contraceptives (birth control pills) Ex. drospirenone, ethinylestradiol Diuretics (medicines used to increase urine output) Ex. bendroflumethiazide, metolazone Medicines used to manage epilepsy (Ex. phenobarbital, phenytoin, carbamazepine) Supplements containing vitamin E or vitamin K B. Drug-Food interaction: Avoid drinking cranberry juice or taking other cranberry products such as capsules or concentrates while taking ACITROM 0.5MG TABLET. Overdosage: If you or anyone else accidentally took more ACITROM 0.5MG TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose might include nosebleeds, bleeding gums, vomiting, or coughing up blood, bloody urine, bloody and black tarry stools, genital bleeding, excessive mensural bleeding, large bruises, bleeding into the joints causing tightness, swelling and pain, increased heartbeat, decreased blood pressure which can make you feel dizzy and can make you skin pale, cold and sweaty. You may also experience vomiting, diarrhea or stomach pain. SYNOPSIS Drug : Nicoumalone Pharmacological Category : Coumarin Derivatives Therapeutic Indication : Blood clot Dosage Forms : Tablet MORE INFORMATIONSTORAGE Keep ACITROM 0.5MG TABLET out of reach of children Store in room temperature
Frequently Asked Questions
Common questions and answers about Acitrom 0.5mg Tablet 10'S.
How to take ACITROM 0.5MG TABLET?
Take ACITROM 0.5MG TABLET as prescribed by your physician. It can be taken at the same time every day. Swallow ACITROM 0.5MG TABLET with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition.
How ACITROM 0.5MG TABLET works on my body?
ACITROM 0.5MG TABLET is a blood thinning medication. It works by preventing the formation of blood clots within the blood vessels. It blocks the actions of certain blood proteins and enzymes that causes blood clots in the body. As a result, it improves the blood flow and oxygen supply through the blood vessels of major organs (heart, brain, and lungs) and improve the symptoms of blood clot disorders.
Is ACITROM 0.5MG TABLET safe to use during pregnancy?
If you are pregnant or think you may be pregnant consult your doctor before taking ACITROM 0.5MG TABLET. ACITROM 0.5MG TABLET has a potential to affect the growing baby and so your doctor will decide whether you should use ACITROM 0.5MG TABLET or not depending upon your health condition.
Can ACITROM 0.5MG TABLET be taken along with alcohol?
No. Avoid consumption of alcohol while taking ACITROM 0.5MG TABLET because it may interfere with its actions and may lead to unwanted side effects.
What can I do if I forget to take ACITROM 0.5MG TABLET on time?
If you forgot to take ACITROM 0.5MG TABLET, take it as soon as you remember. If it’s time for the next dose, skip the missed one and take the next dose on time. Never take a double dose to compensate the missed dose as it could lead to toxicity.
Can I take antibiotics along with ACITROM 0.5MG TABLET?
It is always advisable to consult your doctor before taking any medicines along with ACITROM 0.5MG TABLET. Studies have shown that the use of antibiotics simultaneously with anticoagulants like nicoumalone, increases the risk of bleeding in patients, and so concomitant use of antibiotics along with ACITROM 0.5MG TABLET should be avoided without proper medical supervision.
Why am I not supposed to undergo any surgery while taking ACITROM 0.5MG TABLET?
It is because ACITROM 0.5MG TABLET increases your tendency to bleed. As surgeries are always associated with increased risk of bleeding, concomitant use of ACITROM 0.5MG TABLET with surgeries may make you bleed more than usual. Therefore, it is important to inform your doctor about the use of ACITROM 0.5MG TABLET before undergoing any surgeries (including minor surgeries) to avoid the risk of excessive bleeding.
Is ACITROM 0.5MG TABLET safe to use in children?
ACITROM 0.5MG TABLET should be used with caution in children and adolescents (below 18 years of age). Therefore, consult your doctor for advice before taking.
How long should I take ACITROM 0.5MG TABLET?
You should continue to take ACITROM 0.5MG TABLET unless your doctor tells you to stop. Failure to complete the suggested course may not help you in manageing the condition properly.
What are the side effects caused due to long term use of ACITROM 0.5MG TABLET?
ACITROM 0.5MG TABLET may increase the risk of bleeding. It may make you bleed more easily even after minor cuts, injuries, or wounds, and therefore patients must be advised not to undergo even minor surgeries. It may also cause heavy menstrual period or internal bleeding which can be reflected as blood in vomiting, bloody urine or stools, bloody eyes, or blurred vision. To avoid this your doctor would periodically measure your blood clotting time during management with ACITROM 0.5MG TABLET. Therefore, do not miss your regular hospital visits and take this medicine only as advised by your physician. Consult your doctor if you experience any unusual bleeding over a prolonged period.
How long will it take for ACITROM 0.5MG TABLET to start working?
It may take around 3-4 days for ACITROM 0.5MG TABLET to start working. If immediate blood thinning is necessary, your doctor may prescribe you with other potent anticoagulants (like heparin or warfarin) along with ACITROM 0.5MG TABLET during the initial days. Therefore, consult your doctor for advice.
Article Information
Written By
DETAILS Written By Dr. Janet.C
Medical Content Writer
Reviewed By
Dr. Sankara Babu Gorle
Medical Expert
Last Updated
23 Jul 2024